Concepedia

Mrna Stability

mRNA Stability is the biochemical property that determines the duration of an mRNA molecule's existence in the cytoplasm before degradation, distinguishing it from other regulatory mechanisms by specifically governing the rate of mRNA decay within the post-transcriptional control of gene expression.

4.4K

Publications

386K

Citations

15.1K

Authors

2.6K

Institutions

Publications per year

2017–2026

674

Variants

Messenger Rna Stability

Parents

Children

Publications

4.4K

N6-methyladenosine-dependent regulation of messenger RNA stability

Xiao Wang, Zhike Lu, Adrian Gomez-Nguyen et al. · Nature · 2013 · 4.8K citations

, , +14

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

, , +14

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang, Hengyou Weng, Wenju Sun et al. · Nature Cell Biology · 2018 · 3.1K citations

, , +16

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

Katalin Karikó, Hiromi Muramatsu, Frank A. Welsh et al. · Molecular Therapy · 2008 · 1.9K citations · Full text

, , +17

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

Rickard Sandberg, Joel R. Neilson, Arup Kumar Sarma et al. · Science · 2008 · 1.4K citations · Full text

, , +17

1–5 of 4.4K

Authors

15.1K

  1. RP
    Roy Parker

    Howard Hughes Medical Institute, United States

    42 publications · 8K citations

    38

    h-index

  2. MG
    Myriam Gorospe

    National Institute on Aging, United States

    38 publications · 4.6K citations

    35

    h-index

  3. LE
    Lynne E. Maquat

    University of Rochester, United States

    37 publications · 5.9K citations

    33

    h-index

  4. GB
    Gary Brewer

    Johnson University, United States

    37 publications · 4K citations

    30

    h-index

  5. AJ
    Allan Jacobson

    University of Massachusetts Chan Medical School, United States

    35 publications · 4.2K citations

    29

    h-index

1–5 of 15.1K

Institutions

2.6K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    92 h-index

    372 publications

    105.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    61 h-index

    590 publications

    48.7K citations

  3. Harvard University

    Cambridge, United States

    58 h-index

    289 publications

    41.8K citations

  4. National Institutes of Health

    Bethesda, United States

    56 h-index

    306 publications

    32.2K citations

  5. University of Wisconsin–Madison

    Madison, United States

    52 h-index

    199 publications

    24.9K citations

  6. Johns Hopkins University

    Baltimore, United States

    49 h-index

    181 publications

    24.8K citations

  7. Rutgers, The State University of New Jersey

    New Brunswick, United States

    48 h-index

    246 publications

    27.9K citations

  8. University of Pennsylvania

    Philadelphia, United States

    42 h-index

    180 publications

    33.8K citations

1–8 of 2.6K

Venues

  1. Molecular and Cellular Biology

    MCB · 344 publications · 36.4K citations

    115

    h-index

  2. Journal of Biological Chemistry

    JBC · 349 publications · 28.6K citations

    97

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 158 publications · 20.2K citations

    84

    h-index

  4. Nucleic Acids Research

    252 publications · 18.4K citations

    83

    h-index

  5. Molecular Cell

    89 publications · 15.7K citations

    70

    h-index

1–5