Concepedia

Discovery and optimization of N-acyl and N-aroylpyrazolines as B-Raf kinase inhibitors

Christopher Blackburn, Matthew O. Duffey, Alexandra E. Gould, B. K. KULKARNI, Jane X. Liu, Saurabh Menon, Masayuki Nagayoshi, Tricia J. Vos, Juliet Williams

Bioorganic & Medicinal Chemistry Letters · 2010 · 40 citations · 6 references

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6

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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Gastrosplenic Fistula From Hodgkin's Lymphoma

Carolyn D. Seib, Flavio G. Rocha, Dick G. Hwang et al. · Journal of Clinical Oncology · 2009 · 736 citations

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Suppression of BRAF(V599E) in human melanoma abrogates transformation.

Sunil R. Hingorani, Michael A. Jacobetz, Gavin P. Robertson et al. · PubMed · 2003 · 416 citations

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Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky et al. · Cancer Research · 2006 · 263 citations · Full text

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Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB<sub>1</sub> Cannabinoid Receptor Antagonists

Jos H.M. Lange, Hein K. A. C. Coolen, Herman H. van Stuivenberg et al. · Journal of Medicinal Chemistry · 2003 · 188 citations · Full text

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