Herman H. van Stuivenberg

Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB₁ Cannabinoid Receptor Antagonists

Jos H.M. Lange, Hein K. A. C. Coolen, Herman H. van Stuivenberg et al. · Journal of Medicinal Chemistry · 2003 · 186 citations · Full text

Drug Target, Biological Properties, X-ray Diffraction Study +21

Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant:  Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB₁Cannabinoid Receptor Antagonists

Jos H.M. Lange, Herman H. van Stuivenberg, Hein K. A. C. Coolen et al. · Journal of Medicinal Chemistry · 2004 · 177 citations · Full text

Pyrazole Series, Organic Chemistry, Pharmacotherapy +19

Design, Synthesis and Biological Activity of Rigid Cannabinoid CB1 Receptor Antagonists.

Axel R. Stoit, Jos H.M. Lange, Arnold P. den Hartog et al. · Chemical and Pharmaceutical Bulletin · 2002 · 61 citations · Full text

Pyrazole Ring Closure, Pharmacotherapy, Heterocycle Chemistry +19

Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity

Jos H.M. Lange, Herman H. van Stuivenberg, Willem Veerman et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 61 citations · Full text

Cannabis Use, Molecular Pharmacology, Medicinal Chemistry +12

Synthesis, Structure−Activity Relationships, and Biological Properties of 1-Heteroaryl-4-[ω-(1<i>H</i>-indol-3-yl)alkyl]piperazines, Novel Potential Antipsychotics Combining Potent Dopamine D₂ Receptor Antagonism with Potent Serotonin Reuptake Inhibition

Pieter Smid, Hein K. A. C. Coolen, Hiskias G. Keizer et al. · Journal of Medicinal Chemistry · 2005 · 58 citations · Full text

Psychopharmacology, Biological Properties, Pharmacotherapy +18