Hein K. A. C. Coolen

Author

Solvay (Netherlands)

Also Known As

H. K. A. C. COOLEN, H. K. A. C. Coolen, H.K.A.C Coolen, Hein K. A. C. Coolen, Hein K.A.C. Coolen

Publications

811

Citations

H-Index

Concepts

All Affiliations

Solvay (Netherlands)Radboud University Nijmegen University of Amsterdam

About

Hein K. A. C. Coolen is an author at Solvay (Netherlands) specializing in chemistry, medicine, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	521
2	Natural Sciences	6	6	522
3	Engineering	5	5	195
4	Biochemistry	5	5	509
5	Social Sciences	2	2	80

Hein K. A. C. Coolen

Publications

777

Citations

H-Index

Page 1

	Year	Citations
Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB<sub>1</sub> Cannabinoid Receptor Antagonists Jos H.M. Lange, Hein K. A. C. Coolen, Herman H. van Stuivenberg, Journal of Medicinal Chemistry Drug TargetBiological PropertiesX-ray Diffraction StudyPharmacotherapyMolecular Modeling Investigations	2003	186
Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant: Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB<sub>1</sub>Cannabinoid Receptor Antagonists Jos H.M. Lange, Herman H. van Stuivenberg, Hein K. A. C. Coolen, Journal of Medicinal Chemistry Pyrazole SeriesOrganic ChemistryPharmacotherapyMolecular Modeling InvestigationsChemistry	2004	177
Substrate Selective Catalysis by Rhodium Metallohosts Hein K. A. C. Coolen, Johannes A. M. Meeuwis, Piet W. M. N. van Leeuwen, Journal of the American Chemical Society Inorganic ChemistryChemical EngineeringEngineeringChemical AnalysisSubstrate Selective Catalysis	1995	74
A Rh<sup>I</sup>‐Centered Cage Compound with Selective Catalytic Properties Hein K. A. C. Coolen, Piet W. N. M. van Leeuwen, Roeland J. M. Nolte Angewandte Chemie International Edition in English Inorganic ChemistryEngineeringBiochemistryRh1 Cage CompoundNatural Sciences	1992	67
Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB<sub>1</sub>Receptor Antagonism Jos H.M. Lange, Hein K. A. C. Coolen, Martina A.W. van der Neut, Journal of Medicinal Chemistry	2010	61
Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity Jos H.M. Lange, Herman H. van Stuivenberg, Willem Veerman, Bioorganic & Medicinal Chemistry Letters Cannabis UseMolecular PharmacologyMedicinal ChemistryDrug TargetBiochemistry	2005	61
Synthesis, Structure−Activity Relationships, and Biological Properties of 1-Heteroaryl-4-[ω-(1<i>H</i>-indol-3-yl)alkyl]piperazines, Novel Potential Antipsychotics Combining Potent Dopamine D<sub>2</sub> Receptor Antagonism with Potent Serotonin Reuptake Inhibition Pieter Smid, Hein K. A. C. Coolen, Hiskias G. Keizer, Journal of Medicinal Chemistry PsychopharmacologyBiological PropertiesPharmacotherapyChemistryHeterocycle Chemistry	2005	58
HRh[P(OPh)3]4 as a hydrogenation and isomerization catalyst Hein K. A. C. Coolen, Roeland J. M. Nolte, Piet W. N. M. van Leeuwen Journal of Organometallic Chemistry EngineeringCatalysisHomogeneous CatalysisHydrogenChemistry	1995	23
Principal Component Analysis Differentiates the Receptor Binding Profiles of Three Antipsychotic Drug Candidates from Current Antipsychotic Drugs Jos H.M. Lange, Jan‐Hendrik Reinders, Jeroen Tolboom, Journal of Medicinal Chemistry Current Antipsychotic DrugsDrug TargetPsychotropic MedicationPsychopharmacologyNeuropsychiatry	2007	22
Synthesis and Conformational Behavior of Rhodium(I) Metallohosts Derived from Diphenylglycoluril Hein K. A. C. Coolen, Piet W. N. M. van Leeuwen, Roeland J. M. Nolte The Journal of Organic Chemistry Materials ScienceInorganic ChemistryEngineeringBiochemistryConformational Behavior	1996	18

Page 1