Hein K. A. C. Coolen

Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB₁ Cannabinoid Receptor Antagonists

Jos H.M. Lange, Hein K. A. C. Coolen, Herman H. van Stuivenberg et al. · Journal of Medicinal Chemistry · 2003 · 186 citations · Full text

Drug Target, Biological Properties, X-ray Diffraction Study +21

Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant:  Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB₁Cannabinoid Receptor Antagonists

Jos H.M. Lange, Herman H. van Stuivenberg, Hein K. A. C. Coolen et al. · Journal of Medicinal Chemistry · 2004 · 177 citations · Full text

Pyrazole Series, Organic Chemistry, Pharmacotherapy +19

Substrate Selective Catalysis by Rhodium Metallohosts

Hein K. A. C. Coolen, Johannes A. M. Meeuwis, Piet W. M. N. van Leeuwen et al. · Journal of the American Chemical Society · 1995 · 74 citations

Inorganic Chemistry, Chemical Engineering, Engineering +11

A Rh^I‐Centered Cage Compound with Selective Catalytic Properties

Hein K. A. C. Coolen, Piet W. N. M. van Leeuwen, Roeland J. M. Nolte · Angewandte Chemie International Edition in English · 1992 · 67 citations

Inorganic Chemistry, Engineering, Biochemistry +15

Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB₁Receptor Antagonism

Jos H.M. Lange, Hein K. A. C. Coolen, Martina A.W. van der Neut et al. · Journal of Medicinal Chemistry · 2010 · 61 citations · Full text