Martina A.W. van der Neut

Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity

Antoni R. Blaazer, Jos H.M. Lange, Martina A.W. van der Neut et al. · European Journal of Medicinal Chemistry · 2011 · 72 citations · Full text

Cannabis Use, Psychoactive Drug, Biochemistry +12

Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB₁Receptor Antagonism

Jos H.M. Lange, Hein K. A. C. Coolen, Martina A.W. van der Neut et al. · Journal of Medicinal Chemistry · 2010 · 61 citations · Full text

Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists

Jos H.M. Lange, Arnold P. den Hartog, Martina A.W. van der Neut et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 48 citations · Full text

Cannabis Use, Functional Selectivity, Medicine +4

<i>N</i>′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT₆R) Antagonists with Unique Structural Features

Arnold van Loevezijn, Jennifer Venhorst, Wouter Bakker et al. · Journal of Medicinal Chemistry · 2011 · 44 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies

Jos H.M. Lange, Martina A.W. van der Neut, Henri C. Wals et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 27 citations · Full text

Cannabis Use, Medicinal Chemistry, Drug Target +11