Concepedia

BRAF mutation predicts sensitivity to MEK inhibition

David B. Solit, Levi A. Garraway, Christine A. Pratilas, Ayana Sawai, Gad Getz, Andrea Basso, Qing Ye, Jose Lobo, Yuhong She, Iman Osman,

Nature · 2005 · 1.3K citations · 26 references

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26

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

Todd R. Golub, Donna K. Slonim, Pablo Tamayo et al. · Science · 1999 · 11.6K citations

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Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen et al. · Journal of Biological Chemistry · 1995 · 3.4K citations · Full text

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Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

J. Alan Diehl, Mangeng Cheng, Martine F. Roussel et al. · Genes & Development · 1998 · 2.1K citations · Full text

, , +17

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Levi A. Garraway, Hans R. Widlund, Mark A. Rubin et al. · Nature · 2005 · 1.5K citations

, , +15