Qing Ye

BRAF mutation predicts sensitivity to MEK inhibition

David B. Solit, Levi A. Garraway, Christine A. Pratilas et al. · Nature · 2005 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

^V600E BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway

Christine A. Pratilas, Barry S. Taylor, Qing Ye et al. · Proceedings of the National Academy of Sciences · 2009 · 614 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

Qing‐Bai She, David B. Solit, Qing Ye et al. · Cancer Cell · 2005 · 420 citations

Life Sciences, Molecular Biology, Oncology +16

Propofol and Other Intravenous Anesthetics Have Sites of Action on the γ-Aminobutyric Acid Type A Receptor Distinct from That for Isoflurane

Matthew D. Krasowski, Vladimir V. Koltchine, Caroline Rick et al. · Molecular Pharmacology · 1998 · 254 citations

Medicine, Anesthesiology, Pharmacology +17

SNX2112, a Synthetic Heat Shock Protein 90 Inhibitor, Has Potent Antitumor Activity against HER Kinase–Dependent Cancers

Sarat Chandarlapaty, Ayana Sawai, Qing Ye et al. · Clinical Cancer Research · 2008 · 184 citations

Medicine, Medicinal Chemistry, Pharmacology +14