Concepedia

T-cell co-stimulation by CD28–CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development

M.M. Ewing, Jacco C. Karper, S. Abdul, Rob C. M. de Jong, Hendrika A. B. Peters, Margreet R. de Vries, Anke Redeker, Johan Kuiper, René E. M. Toes, Ramon Arens,

International Journal of Cardiology · 2013 · 128 citations · 28 references

DOI

Concepts

References

28

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

Matthew F. Krummel, James P. Allison · The Journal of Experimental Medicine · 1995 · 2.2K citations · Full text

, , +17

B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

Deborah J. Lenschow, Lesley Rhee, Neda Ashourian et al. · Immunity · 2000 · 2K citations · Full text

, , +16

Natural regulatory T cells control the development of atherosclerosis in mice

Hafid Ait‐Oufella, Benoı̂t L. Salomon, Stéphane Potteaux et al. · Nature Medicine · 2006 · 1.1K citations

, , +12

Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig

Joel M. Kremer, René Westhovens, Marc Léon et al. · New England Journal of Medicine · 2003 · 1.1K citations · Full text

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Monoclonal T-Cell Proliferation and Plaque Instability in Acute Coronary Syndromes

Giovanna Liuzzo, Jörg J. Goronzy, Hongyu Yang et al. · Circulation · 2000 · 556 citations · Full text

, , +16