Expression and purification of soluble porcine CTLA-4 in yeast Pichia pastoris

CTLA-4 Control over Foxp3 ⁺ Regulatory T Cell Function

Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin et al. · Science · 2008 · 2.9K citations

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Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

Kazuhiko Yamada, Koji Yazawa, Akira Shimizu et al. · Nature Medicine · 2004 · 607 citations

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CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics

P. Anton van der Merwe, Dale L. Bodian, Susan Daenke et al. · The Journal of Experimental Medicine · 1997 · 547 citations

Life Sciences, Cell Biology, Immunology +17

Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis

Eduardo H. Garin, Wei Mu, John M. Arthur et al. · Kidney International · 2010 · 191 citations

Medicine, Nephrology, Pathology +8

Gene optimization is necessary to express a bivalent anti-human anti-T cell immunotoxin in Pichia pastoris

Jung Hee Woo, Yuan Yi Liu, Askale Mathias et al. · Protein Expression and Purification · 2002 · 102 citations

Life Sciences, Biotechnology, Immunology +11