Concepedia

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

Keiyo Takubo, Go Nagamatsu, Chiharu I. Kobayashi, Ayako Nakamura‐Ishizu, Hiroshi Kobayashi, Eiji Ikeda, Nobuhito Goda, Yasmeen Rahimi, Randall S. Johnson, Tomoyoshi Soga,

Cell stem cell · 2013 · 794 citations · 39 references

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39

HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

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Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

Margaret A. Goodell, Katja Brose, G Paradis et al. · The Journal of Experimental Medicine · 1996 · 2.9K citations · Full text

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Sheng Zhou, John D. Schuetz, Kevin D. Bunting et al. · Nature Medicine · 2001 · 2.3K citations

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

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Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell · 2004 · 1.9K citations · Full text

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