Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

Anila K. Madiraju, Derek M. Erion, Yasmeen Rahimi, +14

Nature

Mitochondrial FunctionBiochemistryPhysiologyMetabolic RegulationMetabolism +4

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

Keiyo Takubo, Go Nagamatsu, Chiharu I. Kobayashi, +10

Cell stem cell

Pdk FunctionsCell RegulationCell DivisionCell Cycle QuiescenceAutophagy +10

Mutations in <i>BCKD-kinase</i> Lead to a Potentially Treatable Form of Autism with Epilepsy

Gaia Novarino, Paul El-Fishawy, Hülya Kayserili, +19

Science

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

Anila K. Madiraju, Yang Qiu, Rachel J. Perry, +12

Nature Medicine

Redox-dependent MechanismBiochemistryRedox RegulatorPhysiologyReactive Oxygen Specie +4

Bioluminescence-Based Detection of MicroRNA, miR21 in Breast Cancer Cells

Kyle A. Cissell, Yasmeen Rahimi, Suresh Shrestha, +2

Analytical Chemistry

Free Mir21Mir21 MicrornaEngineeringNucleic Acid BiomarkersBioluminescence-based Detection +12

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

Daniel F. Vatner, Sachin Majumdar, Naoki Kumashiro, +9

Proceedings of the National Academy of Sciences

Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler

Rachel J. Perry, Tae-Han Kim, Xian‐Man Zhang, +9

Cell Metabolism

Insulin ResistanceMetabolic SyndromeHepatologyBiochemistryMitochondrial Function +11

Hypophosphatemia promotes lower rates of muscle ATP synthesis

Dominik Pesta, Dimitrios N. Tsirigotis, Douglas E. Befroy, +12

The FASEB Journal

Mechanism of copper induced fluorescence quenching of red fluorescent protein, DsRed

Yasmeen Rahimi, Ann Goulding, Suresh Shrestha, +2

Biochemical and Biophysical Research Communications

Fluorescence QuenchingBiochemistryRed Fluorescent ProteinNatural SciencesMetalloprotein +6

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance

Yasmeen Rahimi, João Paulo Camporez, Max C. Petersen, +5

Proceedings of the National Academy of Sciences