Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

Life Sciences, Genetics, Immunology +14

Molecular and biological characterization of a murine ligand for CD40

Richard J. Armitage, William C. Fanslow, L Strockbine et al. · Nature · 1992 · 1K citations

Life Sciences, Immunology, Molecular Biology +13

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

R J Noelle, Michael Roy, David M. Shepherd et al. · Proceedings of the National Academy of Sciences · 1992 · 810 citations

Life Sciences, Immunology, Molecular Biology +14

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells.

Shulamit Katzav, Dionisio Martı́n-Zanca, Mariano Barbacid · The EMBO Journal · 1989 · 516 citations

Medicine, Molecular Biology, Molecular Genetics +14

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.

Jue Chen, Rusty Lansford, Victoria Stewart et al. · Proceedings of the National Academy of Sciences · 1993 · 407 citations

Life Sciences, Developmental Biology, Genetics +12