Concepedia

B Cell Activation

B Cell Activation is the process by which a naïve B cell, upon recognition of a specific antigen through its B cell receptor and in coordination with helper T cell signals, undergoes clonal expansion and differentiation into antibody-secreting plasma cells or memory B cells, marking the initiation of the humoral immune response.

14.1K

Publications

1M

Citations

51.3K

Authors

5.3K

Institutions

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2017–2026

2K

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Publications

14.1K

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

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B cells and tertiary lymphoid structures promote immunotherapy response

Beth A. Helmink, Sangeetha M. Reddy, Jianjun Gao et al. · Nature · 2020 · 2.7K citations · Full text

, , +16

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

Takashi Nagasawa, Seiichi Hirota, Kazunobu Tachibana et al. · Nature · 1996 · 2.3K citations

, , +15

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

Toshio Hirano, Kiyoshi Yasukawa, Hisashi Harada et al. · Nature · 1986 · 2.2K citations

, , +16

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

Stephen L. Hauser, Amit Bar‐Or, Gavin Giovannoni et al. · New England Journal of Medicine · 2016 · 2K citations · Full text

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1–5 of 14.1K

Authors

51.3K

  1. TK
    Tomohiro Kurosaki

    RIKEN Center for Integrative Medical Sciences, Japan

    93 publications · 11.2K citations

    61

    h-index

  2. KR
    Klaus Rajewsky

    University of Cologne, Germany

    88 publications · 16.2K citations

    58

    h-index

  3. EA
    Edward A. Clark

    University of Washington, United States

    90 publications · 10.7K citations

    56

    h-index

  4. JC
    John C. Cambier

    University of Colorado Denver, United States

    103 publications · 9K citations

    52

    h-index

  5. AS
    Anthony S. Fauci

    National Institute of Allergy and Infectious Diseases, United States

    88 publications · 9.3K citations

    50

    h-index

1–5 of 51.3K

Institutions

5.3K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    131 h-index

    346 publications

    57.1K citations

  2. National Institutes of Health

    Bethesda, United States

    125 h-index

    587 publications

    58.7K citations

  3. Harvard University

    Cambridge, United States

    121 h-index

    426 publications

    47.4K citations

  4. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    104 h-index

    395 publications

    39.9K citations

  5. Inserm

    Paris, France

    104 h-index

    530 publications

    38.9K citations

  6. University of California, San Francisco

    San Francisco, United States

    89 h-index

    201 publications

    29.9K citations

  7. Stanford University

    Stanford, United States

    83 h-index

    218 publications

    28K citations

  8. Yale University

    New Haven, United States

    81 h-index

    212 publications

    26.5K citations

1–8 of 5.3K

Venues

  1. The Journal of Experimental Medicine

    792 publications · 111.6K citations

    183

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  2. The Journal of Immunology

    JI · 2.5K publications · 168.1K citations

    170

    h-index

  3. Blood

    687 publications · 69.4K citations

    140

    h-index

  4. Immunity

    235 publications · 50.3K citations

    136

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 409 publications · 55.4K citations

    126

    h-index

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