Concepedia

B Cell Development

B Cell Development is the process by which hematopoietic progenitor cells undergo lineage-specific differentiation and maturation in primary lymphoid organs to generate functional B lymphocytes capable of producing diverse immunoglobulin receptors through orchestrated genetic rearrangements and selection events.

9.1K

Publications

774.8K

Citations

33K

Authors

3.8K

Institutions

Publications per year

2017–2026

940

Variants

B Cell Differentiation

Parents

Children

Publications

9.1K

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

, , +14

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

, , +10

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

, , +13

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

Takashi Nagasawa, Seiichi Hirota, Kazunobu Tachibana et al. · Nature · 1996 · 2.3K citations

, , +15

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

Toshio Hirano, Kiyoshi Yasukawa, Hisashi Harada et al. · Nature · 1986 · 2.2K citations

, , +16

1–5 of 9.1K

Authors

33K

  1. KR
    Klaus Rajewsky

    University of Cologne, Germany

    130 publications · 23.6K citations

    73

    h-index

  2. FM
    Fritz Melchers

    Institute of Molecular and Clinical Ophthalmology Basel, Switzerland

    95 publications · 10.5K citations

    55

    h-index

  3. FW
    Frederick W. Alt

    Howard Hughes Medical Institute, United States

    79 publications · 11.3K citations

    53

    h-index

  4. MD
    Max D. Cooper

    University of Alabama at Birmingham, United States

    89 publications · 9.9K citations

    51

    h-index

  5. RR
    Richard R. Hardy

    Fox Chase Cancer Center, United States

    57 publications · 11K citations

    43

    h-index

1–5 of 33K

Institutions

3.8K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    139 h-index

    1.2K publications

    229.4K citations

  2. Harvard University

    Cambridge, United States

    103 h-index

    1.3K publications

    152.1K citations

  3. National Institutes of Health

    Bethesda, United States

    93 h-index

    1.1K publications

    153.5K citations

  4. Stanford University

    Stanford, United States

    83 h-index

    780 publications

    96.8K citations

  5. Inserm

    Paris, France

    81 h-index

    1.3K publications

    110.2K citations

  6. University of Alabama at Birmingham

    Birmingham, United States

    77 h-index

    696 publications

    61.4K citations

  7. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    77 h-index

    671 publications

    75K citations

  8. University of Pennsylvania

    Philadelphia, United States

    75 h-index

    704 publications

    71.4K citations

1–8 of 3.8K

Venues

  1. The Journal of Experimental Medicine

    626 publications · 83.7K citations

    160

    h-index

  2. The Journal of Immunology

    JI · 1.5K publications · 94.1K citations

    136

    h-index

  3. Blood

    631 publications · 59.3K citations

    126

    h-index

  4. Immunity

    196 publications · 44.1K citations

    125

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 421 publications · 47.3K citations

    113

    h-index

1–5