Concepedia

E2a Function

E2A Function is a transcriptional regulatory mechanism that directs the specification and differentiation of early B cell lineage by mediating chromatin remodeling and gene expression necessary for B cell commitment.

203

Publications

19.3K

Citations

906

Authors

300

Institutions

Publications per year

2017–2026

18

Parents

Publications

203

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

Gretchen Bain · Cell · 1994 · 766 citations

, , +15

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

Jamison L. Nourse, Julia D. Mellentin, Naomi Galili et al. · Cell · 1990 · 679 citations · Full text

, , +9

The helix-loop-helix gene E2A is required for B cell formation

Yuan Zhuang · Cell · 1994 · 668 citations

, , +10

Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver.

John F. Engelhardt, X Ye, B Doranz et al. · Proceedings of the National Academy of Sciences · 1994 · 626 citations

, , +15

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

Yin C. Lin, Suchit Jhunjhunwala, Christopher Benner et al. · Nature Immunology · 2010 · 511 citations · Full text

, , +15

1–5 of 203

Authors

906

  1. CM
    Cornelis Murre

    University of California San Diego, United States

    23 publications · 3.5K citations

    23

    h-index

  2. YZ
    Yuan Zhuang

    Duke Medical Center, United States

    17 publications · 2.3K citations

    15

    h-index

  3. BL
    Barbara L. Kee

    University of Chicago, United States

    8 publications · 843 citations

    8

    h-index

  4. MS
    Mikael Sigvardsson

    Lund University, Sweden

    8 publications · 1.2K citations

    8

    h-index

  5. DP
    David P. LeBrun

    Queen's University, Canada

    8 publications · 273 citations

    8

    h-index

1–5 of 906

Institutions

300

  1. University of California San Diego

    San Diego, United States

    30 h-index

    113 publications

    19.3K citations

  2. Duke University Hospital

    Durham, United States

    13 h-index

    35 publications

    3.3K citations

  3. Duke Medical Center

    Durham, United States

    13 h-index

    36 publications

    3.3K citations

  4. University of Chicago

    Chicago, United States

    11 h-index

    21 publications

    2.5K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    35 publications

    4.8K citations

  6. Queen's University

    Kingston, Canada

    9 h-index

    47 publications

    1.5K citations

  7. University of Pennsylvania

    Philadelphia, United States

    9 h-index

    36 publications

    6K citations

  8. Stanford University

    Stanford, United States

    8 h-index

    28 publications

    4.8K citations

1–8 of 300

Venues

  1. Molecular and Cellular Biology

    MCB · 41 publications · 4.4K citations

    34

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 2K citations

    15

    h-index

  3. The Journal of Immunology

    JI · 13 publications · 525 citations

    13

    h-index

  4. The Journal of Experimental Medicine

    11 publications · 1.4K citations

    11

    h-index

  5. Blood

    9 publications · 628 citations

    9

    h-index

1–5