David M. Shepherd

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

R J Noelle, Michael Roy, David M. Shepherd et al. · Proceedings of the National Academy of Sciences · 1992 · 809 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +21

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

Teresa M. Foy, David M. Shepherd, Fiona H. Durie et al. · The Journal of Experimental Medicine · 1993 · 353 citations · Full text

Immunology, Immunologic Mechanism, Antigen Processing +17

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions.

Alfons J. van den Eertwegh, Randolph J. Noelle, Michael Roy et al. · The Journal of Experimental Medicine · 1993 · 249 citations · Full text

Lymphocyte Development, Adaptive Immune System, T-regulatory Cell +18

Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells

Ava Rhule, Séverine Navarro, Jerry R. Smith et al. · Journal of Ethnopharmacology · 2006 · 165 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +5

Aryl Hydrocarbon Receptor Activation by TCDD Reduces Inflammation Associated with Crohn's Disease

Jenna M. Benson, David M. Shepherd · Toxicological Sciences · 2010 · 161 citations · Full text

Chronic Inflammatory Diseases, Tcdd-treated Mice, Gut Bacteria +20