Concepedia

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

Alexis M. Kalergis, Nicole Boucheron, Marie‐Agnès Doucey, Edith Palmieri, Earl Goyarts, Zsuzsanna Végh, Immanuel F. Luescher, Stanley G. Nathenson

Nature Immunology · 2001 · 324 citations · 43 references

DOI

Concepts

References

43

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations

, , +16

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

Salvatore Valitutti, Sabina Müller, Marina Cella et al. · Nature · 1995 · 1.1K citations

, , +16

Kinetic proofreading in T-cell receptor signal transduction.

Timothy W. McKeithan · Proceedings of the National Academy of Sciences · 1995 · 985 citations

, , +17

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

Yuri Sykulev, Michael Joo, Irina Vturina et al. · Immunity · 1996 · 706 citations · Full text

, , +16

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

Grada M. van Bleek, Stanley G. Nathenson · Nature · 1990 · 683 citations

, , +9