Salvatore Valitutti

Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau et al. · Nature Immunology · 2000 · 1.9K citations

Life Sciences, Cell Biology, Molecular Biology +14

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

Salvatore Valitutti, Sabina Müller, Marina Cella et al. · Nature · 1995 · 1.1K citations

Life Sciences, Immunology, Molecular Biology +16

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton.

Salvatore Valitutti, Mark C. Dessing, Klaus Aktories et al. · The Journal of Experimental Medicine · 1995 · 526 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

Salvatore Valitutti, Sabina Müller, Mark C. Dessing et al. · The Journal of Experimental Medicine · 1996 · 438 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +16

A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion in CD4+ T Cells

Jun Huang, Mario Brameshuber, Xun Zeng et al. · Immunity · 2013 · 399 citations · Full text

Life Sciences, Immunology, Molecular Biology +12