Concepedia

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

Salvatore Valitutti, Sabina Müller, Marina Cella, Elisabetta Padovan, Antonio Lanzavecchia

Nature · 1995 · 1.1K citations · 22 references

DOI

Concepts

References

22

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

Paola Panina‐Bordignon, Agnes L. Tan, A. Termijtelen et al. · European Journal of Immunology · 1989 · 712 citations

, , +16

Partial T cell signaling: Altered phospho-? and lack of zap70 recruitment in APL-induced T cell anergy

Joanne Sloan‐Lancaster · Cell · 1994 · 595 citations

, , +16

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

Elisabetta Padovan, Giulia Casorati, Paolo Dellabona et al. · Science · 1993 · 550 citations

, , +16

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton.

Salvatore Valitutti, Mark C. Dessing, Klaus Aktories et al. · The Journal of Experimental Medicine · 1995 · 526 citations · Full text

, , +17

ζ Phosphorylation Without ZAP-70 Activation Induced by TCR Antagonists or Partial Agonists

Joaquı́n Madrenas, Ronald L. Wange, Jennifer L. Wang et al. · Science · 1995 · 502 citations

, , +17