Yuri Sykulev

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

Yuri Sykulev, Michael Joo, Irina Vturina et al. · Immunity · 1996 · 700 citations · Full text

Single Peptide–mhc Complex, Immune Effector Functions, Immune Regulation +10

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

Yuri Sykulev, Anders Brunmark, Michael R. Jackson et al. · Immunity · 1994 · 252 citations

Signal Transduction, Biochemistry, T-regulatory Cell +10

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.

Yuri Sykulev, Anders Brunmark, Theodore J. Tsomides et al. · Proceedings of the National Academy of Sciences · 1994 · 198 citations · Full text

Histocompatibility, Immunology, Immunodominance +20

Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes

Nadia Anikeeva, Kristina Somersalo, Tasha N. Sims et al. · Proceedings of the National Academy of Sciences · 2005 · 183 citations · Full text

Cytotoxic T Lymphocytes, Cell Adhesion, T-regulatory Cell +19

Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses.

Shigeki Kageyama, Theodore J. Tsomides, Yuri Sykulev et al. · The Journal of Immunology · 1995 · 144 citations

Mhc Class, Adaptive Immune System, Immunology +17