A liquid chromatography/mass spectrometry-based generic detection method for biochemical assay and hit discovery of histone methyltransferases

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

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Life Sciences, Genetics, Molecular Biology +11

Histone demethylation by a family of JmjC domain-containing proteins

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Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists.

Robert A. Copeland · PubMed · 2005 · 1.1K citations

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Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

Scott R. Daigle, Edward J. Olhava, Carly A. Therkelsen et al. · Cancer Cell · 2011 · 934 citations · Full text

Medicine, Medicinal Chemistry, Oncology +10