Kehao Zhao

Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks

Frank W. Schmitges, Archana Bairavasundaram Prusty, Mahamadou Faty et al. · Molecular Cell · 2011 · 734 citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +14

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

Wei Qi, Homan Chan, Lin Teng et al. · Proceedings of the National Academy of Sciences · 2012 · 542 citations · Full text

Selective Inhibition, Tumor Biology, Methyl Group +15

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

Xin Liu, Ling Wang, Kehao Zhao et al. · Nature · 2008 · 440 citations

Transcriptional Regulation, Protein Expression, Biochemistry +9

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Wei Qi, Kehao Zhao, Justin Gu et al. · Nature Chemical Biology · 2017 · 313 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Structure of the Human Papillomavirus E7 Oncoprotein and Its Mechanism for Inactivation of the Retinoblastoma Tumor Suppressor

Xin Liu, Adrienne Clements, Kehao Zhao et al. · Journal of Biological Chemistry · 2005 · 233 citations · Full text

Prb Binding, Cell Regulation, Cell Signaling +15