Concepedia

Histone Methyltransferases

Histone Methyltransferases is an enzyme class that catalyzes the transfer of methyl groups to specific lysine or arginine residues on histone proteins, thereby regulating chromatin structure and gene expression through covalent post-translational modification.

2.2K

Publications

203.3K

Citations

13K

Authors

2.2K

Institutions

Publications per year

2017–2026

747

Variants

Histone MethyltransferaseHmts

Parents

Publications

2.2K

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Stephen Rea, Frank Eisenhaber, Dónal O’Carroll et al. · Nature · 2000 · 2.8K citations

, , +14

Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability

Antoine H.F.M. Peters, Dónal O’Carroll, Harry Scherthan et al. · Cell · 2001 · 1.8K citations · Full text

, , +12

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Ryan D. Morin, María Méndez-Lago, Andrew J. Mungall et al. · Nature · 2011 · 1.6K citations · Full text

, , +17

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Steen K.T. Ooi, Chen Qiu, Emily Bernstein et al. · Nature · 2007 · 1.6K citations · Full text

, , +15

Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex

Jürg Müller, Craig M. Hart, Nicole J. Francis et al. · Cell · 2002 · 1.6K citations · Full text

, , +14

1–5 of 2.2K

Authors

13K

  1. YS
    Yoichi Shinkai

    Kyoto University, Japan

    32 publications · 6.6K citations

    27

    h-index

  2. MV
    Masoud Vedadi

    Structural Genomics Consortium, Canada

    29 publications · 2.8K citations

    25

    h-index

  3. TJ
    Thomas Jenuwein

    Research Institute of Molecular Pathology, Austria

    23 publications · 10.7K citations

    23

    h-index

  4. CD
    C. David Allis

    Rockefeller University, United States

    23 publications · 13.3K citations

    23

    h-index

  5. MT
    Makoto Tachibana

    Kyoto University, Japan

    22 publications · 4.8K citations

    21

    h-index

1–5 of 13K

Institutions

2.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    61 h-index

    194 publications

    48.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    45 h-index

    341 publications

    30.7K citations

  3. Harvard University

    Cambridge, United States

    43 h-index

    251 publications

    56.9K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    41 h-index

    194 publications

    30.9K citations

  5. Chinese Academy of Sciences

    Beijing, China

    38 h-index

    321 publications

    24.7K citations

  6. University of Toronto

    Toronto, Canada

    38 h-index

    362 publications

    50.5K citations

  7. National Institutes of Health

    Bethesda, United States

    37 h-index

    212 publications

    29.3K citations

  8. University of California, Los Angeles

    Los Angeles, United States

    35 h-index

    147 publications

    40.4K citations

1–8 of 2.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 140 publications · 15.8K citations

    70

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 67 publications · 8.8K citations

    48

    h-index

  3. Molecular and Cellular Biology

    MCB · 59 publications · 8.2K citations

    44

    h-index

  4. PLoS ONE

    72 publications · 4.2K citations

    39

    h-index

  5. Nucleic Acids Research

    57 publications · 4.6K citations

    39

    h-index

1–5