Masoud Vedadi

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

Protein Chemistry, Protein Stability, Biochemistry +9

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

Masoud Vedadi, F. Niesen, Abdellah Allali‐Hassani et al. · Proceedings of the National Academy of Sciences · 2006 · 589 citations · Full text

New Ligands, Protein Assembly, Molecular Biology +21

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu et al. · Nature Chemical Biology · 2011 · 527 citations

Signal Transduction, Cellular Enzymology, Biochemistry +12

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Jiajun Zhu, Morgan A. Sammons, Greg Donahue et al. · Nature · 2015 · 482 citations · Full text

Cancer Research, Chromatin, Chromatin Remodeling +10

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Kyle D. Konze, Anqi Ma, Fengling Li et al. · ACS Chemical Biology · 2013 · 464 citations · Full text

Histone Modifications, Epigenetic Change, Molecular Biology +20