F. Niesen

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

Protein Chemistry, Protein Stability, Biochemistry +9

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

Masoud Vedadi, F. Niesen, Abdellah Allali‐Hassani et al. · Proceedings of the National Academy of Sciences · 2006 · 589 citations · Full text

New Ligands, Protein Assembly, Molecular Biology +21

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

P. Rellos, A.C.W. Pike, F. Niesen et al. · PLoS Biology · 2010 · 302 citations · Full text

Kinase Inhibitor Selectivity Profiling Using Differential Scanning Fluorimetry

O. Fedorov, F. Niesen, Stefan Knapp · Methods in molecular biology · 2011 · 174 citations

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

A.C.W. Pike, P. Rellos, F. Niesen et al. · The EMBO Journal · 2008 · 168 citations · Full text

Signal Transduction, Activation Segment Dimerization, Signaling Pathway +12