Concepedia
Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations · 11 references
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PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoverySynthetic Medicinal ChemistryPotency Optimization
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The capsaicin receptor: a heat-activated ion channel in the pain pathway
Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9.1K citations
Life Sciences, Neurobiology, Pharmacology +16
The VR1 Antagonist Capsazepine Reverses Mechanical Hyperalgesia in Models of Inflammatory and Neuropathic Pain
Katharine Walker, László Urbán, Stephen J. Medhurst et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 347 citations
Nursing, Pharmacology, Pain Medicine +16
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist
Martin J. Gunthorpe, Harshad K. Rami, Jeffrey C. Jerman et al. · Neuropharmacology · 2003 · 273 citations
Medicine, Medicinal Chemistry, Pharmacology +11
Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development
Harshad K. Rami, Mervyn Thompson, Geoffrey Stemp et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 132 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +5
Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells
Martin J. Gunthorpe, Gary D. Smith, Janet L. Davis et al. · Pflügers Archiv - European Journal of Physiology · 2001 · 116 citations
Natural Sciences, Cell Biology, Molecular Biology +14