Sarah C. Lappin

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist

Martin J. Gunthorpe, Harshad K. Rami, Jeffrey C. Jerman et al. · Neuropharmacology · 2003 · 272 citations

Biochemistry, Functional Selectivity, Selective Vanilloid Receptor +6

Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor

Martin J. Gunthorpe, Sara Luis Hannan, Darren Smart et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 103 citations

TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation

Sarah C. Lappin, Andrew D. Randall, Martin J. Gunthorpe et al. · European Journal of Pharmacology · 2006 · 70 citations

Inflammation, Medicine, Synaptic Transmission +12

Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1

Susan M. Westaway, Mervyn Thompson, Harshad K. Rami et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Derivative (Chemistry) +8

Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons

Sarah C. Lappin, Tim Dale, Jon T. Brown et al. · Brain Research · 2005 · 37 citations

Neurodynamics, Neurophysiology, Medicine +10