Tim Dale

Population patch clamp electrophysiology: a breakthrough technology for ion channel screening

Tim Dale, Claire Townsend, Emma C. Hollands et al. · Molecular BioSystems · 2007 · 56 citations

Biomedical Engineering, Social Sciences, Electrophysiological Evaluation +19

Novel 384-Well Population Patch Clamp Electrophysiology Assays for Ca2+-Activated K+ Channels

Victoria H. John, Tim Dale, Emma C. Hollands et al. · SLAS DISCOVERY · 2006 · 43 citations · Full text

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding

Holger Scheib, Iain M. McLay, Nicolas Guex et al. · Journal of Molecular Modeling · 2006 · 42 citations

Pore Structure, Molecular Physiology, Local Anesthetic Binding +13

Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons

Sarah C. Lappin, Tim Dale, Jon T. Brown et al. · Brain Research · 2005 · 37 citations

Neurodynamics, Neurophysiology, Medicine +10

The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo

Sara Strese, Malin Wickström, Peder Fredlund Fuchs et al. · Biochemical Pharmacology · 2013 · 34 citations

Inflammation, Anti-inflammatory, Angiogenesis +9