Iain M. McLay - Concepedia

Concepedia

Author

Iain M. McLay

GlaxoSmithKline (United Kingdom)

Also Known As

I. M. MCLAY, I. McLay, I. Mclay, I.M. McLay, Iain M McLay, Iain M. McLay, Iain M. Mclay, Iain McLay, Iain Mclay

47

Publications

2.1K

Citations

24

H-Index

69

Concepts

All Affiliations

GlaxoSmithKline (United Kingdom)Barking and Dagenham College GlaxoSmithKline (United States)Research Triangle Park Foundation University of Sheffield

IM

About

Iain M. McLay is an author at GlaxoSmithKline (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	20	24	1.7K
2	Natural Sciences	13	14	775
3	Engineering	6	6	735
4	Social Sciences	1	1	42
5	Allergy	1	1	77

Iain M. McLay

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34

Publications

2.1K

Citations

24

H-Index

	Year	Citations
GRid-INdependent Descriptors (GRIND): A Novel Class of Alignment-Independent Three-Dimensional Molecular Descriptors Manuel Pastor, Gabriele Cruciani, Iain M. McLay, Journal of Medicinal Chemistry EngineeringStructural BioinformaticsMolecular BiologySequence AlignmentMolecular Graphic	2000	464
Diversity Profiling and Design Using 3D Pharmacophores: Pharmacophore-Derived Queries (PDQ) Stephen D. Pickett, Jonathan Mason, Iain M. McLay Journal of Chemical Information and Computer Sciences Combinatorial ChemistryBioorganic ChemistryMedicinal ChemistryLead GenerationDrug Design	1996	154
X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain Keith Biggadike, Randy K. Bledsoe, Anne M. Hassell, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryBiochemistryG Protein-coupled ReceptorMedicine	2008	112
Enhancing the Hit-to-Lead Properties of Lead Optimization Libraries Stephen D. Pickett, Iain M. McLay, David E. Clark Journal of Chemical Information and Computer Sciences Lead ConversionDrug TargetEngineeringHit IdentificationLead Identification	1999	100
Synthesis and Structure−Activity Relationships of Long-acting β<sub>2</sub>Adrenergic Receptor Agonists Incorporating Metabolic Inactivation: An Antedrug Approach Panayiotis A. Procopiou, Victoria J. Barrett, Nicola Bevan, Journal of Medicinal Chemistry	2010	98
Progesterone Receptor Ligand Binding Pocket Flexibility: Crystal Structures of the Norethindrone and Mometasone Furoate Complexes Kevin P. Madauss, Su-Jun Deng, Robert J. Austin, Journal of Medicinal Chemistry Progesterone ReceptorPeptide ScienceActive Af2 ConformationChemical BiologyProgesterone Complex	2004	86
Similarity Measures for Rational Set Selection and Analysis of Combinatorial Libraries: The Diverse Property-Derived (DPD) Approach Richard A. Lewis, Jonathan Mason, Iain M. McLay Journal of Chemical Information and Computer Sciences	1997	82
Knowledge-Based Interaction Fingerprint Scoring: A Simple Method for Improving the Effectiveness of Fast Scoring Functions Chidochangu P. Mpamhanga, Beining Chen, Iain M. McLay, Journal of Chemical Information and Modeling	2006	80
Dissociated Nonsteroidal Glucocorticoid Receptor Modulators; Discovery of the Agonist Trigger in a Tetrahydronaphthalene−Benzoxazine Series Mike D. Barker, Margaret Clackers, Royston C. B. Copley, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryTetrahydronaphthalene-benzoxazine Glucocorticoid ReceptorAllergyFunctional Selectivity	2006	77
An Algorithm-Directed Two-Component Library Synthesized Via Solid-Phase Methodology Yielding Potent and Orally Bioavailable p38 MAP Kinase Inhibitors Jeffrey M. McKenna, Frank Halley, John E. Souness, Journal of Medicinal Chemistry Combinatorial ChemistryMedicinal ChemistryDrug TargetBioorganic ChemistryPermeability Assays	2002	73

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