Iain M. McLay

GRid-INdependent Descriptors (GRIND):  A Novel Class of Alignment-Independent Three-Dimensional Molecular Descriptors

Manuel Pastor, Gabriele Cruciani, Iain M. McLay et al. · Journal of Medicinal Chemistry · 2000 · 464 citations · Full text

Pharmacy, Medicinal Chemistry, Computational Chemistry +14

Diversity Profiling and Design Using 3D Pharmacophores:  Pharmacophore-Derived Queries (PDQ)

Stephen D. Pickett, Jonathan Mason, Iain M. McLay · Journal of Chemical Information and Computer Sciences · 1996 · 154 citations

Pharmacy, Medicinal Chemistry, Combinatorial Chemistry +16

X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain

Keith Biggadike, Randy K. Bledsoe, Anne M. Hassell et al. · Journal of Medicinal Chemistry · 2008 · 112 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Enhancing the Hit-to-Lead Properties of Lead Optimization Libraries

Stephen D. Pickett, Iain M. McLay, David E. Clark · Journal of Chemical Information and Computer Sciences · 1999 · 100 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and Structure−Activity Relationships of Long-acting β₂Adrenergic Receptor Agonists Incorporating Metabolic Inactivation: An Antedrug Approach

Panayiotis A. Procopiou, Victoria J. Barrett, Nicola Bevan et al. · Journal of Medicinal Chemistry · 2010 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16