Stephen D. Pickett

Computational methods for the prediction of ‘drug-likeness’

David E. Clark, Stephen D. Pickett · Drug Discovery Today · 2000 · 573 citations

Pharmacy, Bioinformatics, Medicinal Chemistry +14

GRid-INdependent Descriptors (GRIND):  A Novel Class of Alignment-Independent Three-Dimensional Molecular Descriptors

Manuel Pastor, Gabriele Cruciani, Iain M. McLay et al. · Journal of Medicinal Chemistry · 2000 · 464 citations · Full text

Pharmacy, Medicinal Chemistry, Computational Chemistry +14

Empirical Scale of Side-Chain Conformational Entropy in Protein Folding

Stephen D. Pickett, Michael J.E. Sternberg · Journal of Molecular Biology · 1993 · 260 citations

Life Sciences, Biochemistry, Biophysics +16

Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia

György M. Keserű, Daniel A. Erlanson, György G. Ferenczy et al. · Journal of Medicinal Chemistry · 2016 · 233 citations

Pharmacy, Medicinal Chemistry, Drug Design +16

The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?

Timothy J. Ritchie, Simon J. F. Macdonald, Simon Peace et al. · MedChemComm · 2012 · 178 citations

Pharmacy, Chemistry, Pharmacology +6