Concepedia

A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification

Whitney M. Nolte, Jean‐Philippe Fortin, Benjamin D. Stevens, Gary E. Aspnes, David A. Griffith, Lise R. Hoth, Roger B. Ruggeri, Alan M. Mathiowetz, Chris Limberakis, David Hepworth,

Nature Chemical Biology · 2014 · 87 citations · 15 references

DOI

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References

15

Structure of the human glucagon class B G-protein-coupled receptor

Fai Siu, Min He, Chris de Graaf et al. · Nature · 2013 · 377 citations · Full text

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Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

Cassandra Koole, Denise Wootten, John Simms et al. · Molecular Pharmacology · 2010 · 226 citations

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GLP-1 Mediates Antiapoptotic Effect by Phosphorylating Bad through a β-Arrestin 1-mediated ERK1/2 Activation in Pancreatic β-Cells

Julie Quoyer, Christine Longuet, Christophe Broca et al. · Journal of Biological Chemistry · 2009 · 184 citations · Full text

, , +17

Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

Kyle W. Sloop, Francis S. Willard, Martin Brenner et al. · Diabetes · 2010 · 140 citations · Full text

, , +17

Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon

Simon A. Hinke, J. Andrew Pospisilik, Hans-Ulrich Demuth et al. · Journal of Biological Chemistry · 2000 · 120 citations · Full text

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