Chris de Graaf

Structure of the human glucagon class B G-protein-coupled receptor

Fai Siu, Min He, Chris de Graaf et al. · Nature · 2013 · 377 citations · Full text

Life Sciences, Biochemistry, Endocrinology +8

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason et al. · Nature Communications · 2019 · 363 citations · Full text

Medicine, Oncology, Pharmacology +16

KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space

Oscar P. J. van Linden, Albert J. Kooistra, Rob Leurs et al. · Journal of Medicinal Chemistry · 2013 · 311 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

Ligand efficiency as a guide in fragment hit selection and optimization

Sabine Schultes, Chris de Graaf, Eric Haaksma et al. · Drug Discovery Today Technologies · 2010 · 249 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +15

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Gaojie Song, Dehua Yang, Yuxia Wang et al. · Nature · 2017 · 244 citations

Life Sciences, Biochemistry, Molecular Biology +12