Chris de Graaf

Structure of the human glucagon class B G-protein-coupled receptor

Fai Siu, Min He, Chris de Graaf et al. · Nature · 2013 · 373 citations · Full text

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +6

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason et al. · Nature Communications · 2019 · 350 citations · Full text

KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space

Oscar P. J. van Linden, Albert J. Kooistra, Rob Leurs et al. · Journal of Medicinal Chemistry · 2013 · 297 citations · Full text

Signal Transduction Pathways, Engineering, Structural Bioinformatics +18

Ligand efficiency as a guide in fragment hit selection and optimization

Sabine Schultes, Chris de Graaf, Eric Haaksma et al. · Drug Discovery Today Technologies · 2010 · 241 citations · Full text

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Gaojie Song, Dehua Yang, Yuxia Wang et al. · Nature · 2017 · 240 citations

Allosteric Modulators, Signal Transduction, Molecular Physiology +9