Sabine Schultes

Ligand efficiency as a guide in fragment hit selection and optimization

Sabine Schultes, Chris de Graaf, Eric Haaksma et al. · Drug Discovery Today Technologies · 2010 · 249 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +15

Detailed analysis of biased histamine<scp>H</scp><scp>₄</scp>receptor signalling by<scp>JNJ</scp>7777120 analogues

Saskia Nijmeijer, Henry F. Vischer, Francesco Sirci et al. · British Journal of Pharmacology · 2013 · 39 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Design and pharmacological characterization of <scp>VUF14480</scp>, a covalent partial agonist that interacts with cysteine 98^3.36 of the human histamine <scp>H₄</scp> receptor

Saskia Nijmeijer, Harald Engelhardt, Sabine Schultes et al. · British Journal of Pharmacology · 2013 · 32 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds

Sabine Schultes, Chris de Graaf, Helmut Berger et al. · MedChemComm · 2012 · 27 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Mapping histamine H₄receptor–ligand binding modes

Sabine Schultes, Saskia Nijmeijer, Harald Engelhardt et al. · MedChemComm · 2012 · 26 citations

Medicine, Molecular Biology, Pharmacology +17