Concepedia

Author

Francesco Sirci

Telethon Institute Of Genetics And MedicineORCID

Also Known As

F Sirci, Francesco Sirci

24

Publications

720

Citations

13

H-Index

23

Concepts

All Affiliations

Telethon Institute Of Genetics And MedicineUniversity of Naples Federico IIVrije Universiteit AmsterdamUniversity of PerugiaHeinrich Heine University Düsseldorf
FS

About

Francesco Sirci is an author at Telethon Institute Of Genetics And Medicine specializing in medicine, molecular pharmacology, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

216

2

Biochemistry

4

4

148

3

Natural Sciences

3

3

152

4

Engineering

1

1

16

5

Cellular Physiology

1

1

16

Francesco Sirci

×

12

Publications

677

Citations

12

H-Index

YearCitations

gene2drug: a computational tool for pathway-based rational drug repositioning

Francesco Napolitano, Diego Carrella, Barbara Mandriani,

Bioinformatics

2017

101

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release

Giulia Gorrieri, Paolo Scudieri, Emanuela Caci,

Scientific Reports

2016

89

Mantra 2.0: an online collaborative resource for drug mode of action and repurposing by network analysis

Diego Carrella, Francesco Napolitano, Rossella Rispoli,

Bioinformatics

2014

86

Drug-set enrichment analysis: a novel tool to investigate drug mode of action

Francesco Napolitano, Francesco Sirci, Diego Carrella,

Bioinformatics

2015

84

Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists

Maikel Wijtmans, David Maussang, Francesco Sirci,

European Journal of Medicinal Chemistry

2012

68

Virtual Fragment Screening: Discovery of Histamine H<sub>3</sub> Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints

Francesco Sirci, Enade Perdana Istyastono, Henry F. Vischer,

Journal of Chemical Information and Modeling

2012

64

Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A1, A2A, A2B, and A3 receptor antagonists

Francesco Sirci, Laura Goracci, David Rodríguez,

Journal of Computer-Aided Molecular Design

2012

48

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds

Diego Carrella, Isabella Manni, Barbara Tumaini,

Oncotarget

2016

47

Detailed analysis of biased histamine<scp>H</scp><scp><sub>4</sub></scp>receptor signalling by<scp>JNJ</scp>7777120 analogues

Saskia Nijmeijer, Henry F. Vischer, Francesco Sirci,

British Journal of Pharmacology

2013

39

Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses

Francesco Sirci, Francesco Napolitano, Sandra Pisonero‐Vaquero,

npj Systems Biology and Applications

2017

20

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