Concepedia

Allosteric Interactions

Allosteric Interactions is a biochemical mechanism in which the binding of a ligand at an allosteric site modulates the functional activity of a protein at a distinct, topographically separate active site through conformational changes.

691

Publications

48.4K

Citations

2.8K

Authors

763

Institutions

Publications per year

2017–2026

132

Parents

Publications

691

On the nature of allosteric transitions: A plausible model

Jacques Monod, Jeffries Wyman, Jean‐Pierre Changeux · Journal of Molecular Biology · 1965 · 8.9K citations

, , +10

Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism

J.M. Baldwin, Cyrus Chothia · Journal of Molecular Biology · 1979 · 867 citations

, , +14

Mechanisms of cooperativity and allosteric regulation in proteins

M. F. Perutz · Quarterly Reviews of Biophysics · 1989 · 636 citations

, , +12

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

Barry M. Forman, Kazuhiko Umesono, Jasmine Chen et al. · Cell · 1995 · 632 citations · Full text

, , +16

Allosteric sodium in class A GPCR signaling

Vsevolod Katritch, Gustavo Fenalti, Enrique E. Abola et al. · Trends in Biochemical Sciences · 2014 · 519 citations · Full text

, , +14

1–5 of 691

Authors

2.8K

  1. GM
    Gennady M. Verkhivker

    Chapman University, United States

    20 publications · 963 citations

    17

    h-index

  2. MF
    Michael F. Dunn

    University of California, Riverside, United States

    12 publications · 400 citations

    11

    h-index

  3. NB
    N.J.M. Birdsall

    National Institute for Medical Research, Tanzania

    8 publications · 709 citations

    8

    h-index

  4. JE
    John E. Ellis

    University of Minnesota, United States

    8 publications · 418 citations

    8

    h-index

  5. AC
    Arthur Christopoulos

    Monash University, Australia

    8 publications · 343 citations

    8

    h-index

1–5 of 2.8K

Institutions

763

  1. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    70 publications

    5.4K citations

  2. Chapman University

    Orange, United States

    17 h-index

    46 publications

    1.9K citations

  3. National Institutes of Health

    Bethesda, United States

    17 h-index

    76 publications

    4.6K citations

  4. Harvard University

    Cambridge, United States

    16 h-index

    41 publications

    2.7K citations

  5. University of California San Diego

    San Diego, United States

    13 h-index

    30 publications

    3.7K citations

  6. Inserm

    Paris, France

    13 h-index

    54 publications

    2.7K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    30 publications

    6.7K citations

  8. University of Washington

    Seattle, United States

    11 h-index

    48 publications

    4.4K citations

1–8 of 763

Venues

  1. Biochemistry

    78 publications · 3.4K citations

    34

    h-index

  2. Journal of Biological Chemistry

    JBC · 60 publications · 2.8K citations

    33

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 3.6K citations

    31

    h-index

  4. Molecular Pharmacology

    36 publications · 2.5K citations

    28

    h-index

  5. Journal of Molecular Biology

    JMB · 40 publications · 12.2K citations

    27

    h-index

1–5