Nature Biotechnology · 2014 · 705 citations · 22 references
Life SciencesGeneticsMolecular BiologyGenetic EngineeringGenome EditingGenomicsCrispr-based EngineeringCrispr-cas SystemsGuide Rna DesignMalariaMalaria Vector BiologyTherapeutic Genome EditingCrispr-based Genome EngineeringCrispr-cas Genome EditingCrispr-cas9 Genome EditingCrispr-cas9-mediated RepairGenome Editing In PathogensPlasmodium FalciparumSingle-guide Rna Design
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert, Matthew H. Larson, Leonardo Morsut et al. · Cell · 2013 · 3.8K citations · Full text