Concepedia

Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation

Yuji Kubota, P. O’Grady, Haruo Saito, Mutsuhiro Takekawa

Nature Cell Biology · 2011 · 69 citations · 44 references

DOI

Concepts

References

44

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

Sally A. Cowley · Cell · 1994 · 2K citations

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

Poulikos I. Poulikakos, Chao Zhang, Gideon Bollag et al. · Nature · 2010 · 1.8K citations · Full text

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Plat-E: an efficient and stable system for transient packaging of retroviruses

S. Morita, T Kojima, Toshio Kitamura · Gene Therapy · 2000 · 1.7K citations

, , +9

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations

, , +15

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Sonja J. Heidorn, Carla Milagre, Steven R. Whittaker et al. · Cell · 2010 · 1.5K citations · Full text

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