Concepedia

Poulikos I. Poulikakos

PI

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Publications

30

Citations

8.1K

H-Index

27

Active since

2001

Affiliations

Icahn School of Medicine at Mount Sinai(Current)

Memorial Sloan Kettering Cancer Center

Tisch Hospital

Fox Chase Cancer Center

Texas Children's Hospital

Poulikos I. Poulikakos is an author at Icahn School of Medicine at Mount Sinai specializing in medicine, cell biology, and cell signaling.

ORCID

Top concepts

Publications per year

2001–2022

30

Publications

30

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

Poulikos I. Poulikakos, Chao Zhang, Gideon Bollag et al. · Nature · 2010 · 1.8K citations · Full text

, , +10

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

Poulikos I. Poulikakos, Yogindra Persaud, Manickam Janakiraman et al. · Nature · 2011 · 1.4K citations

, , +1

Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas

Piro Lito, Christine A. Pratilas, Eric W. Joseph et al. · Cancer Cell · 2012 · 551 citations · Full text

, , +11

BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

Zhan Yao, Neilawattie M. Torres, Anthony Tao et al. · Cancer Cell · 2015 · 537 citations · Full text

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Eric W. Joseph, Christine A. Pratilas, Poulikos I. Poulikakos et al. · Proceedings of the National Academy of Sciences · 2010 · 446 citations · Full text

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