Yogindra Persaud

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

Poulikos I. Poulikakos, Yogindra Persaud, Manickam Janakiraman et al. · Nature · 2011 · 1.4K citations

Medicine, Molecular Biology, Oncology +9

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Eric W. Joseph, Christine A. Pratilas, Poulikos I. Poulikakos et al. · Proceedings of the National Academy of Sciences · 2010 · 447 citations · Full text

Medicine, Cancer Biology, Oncology +15

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

Manickam Janakiraman, Efsevia Vakiani, Zhaoshi Zeng et al. · Cancer Research · 2010 · 285 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Genetic Predictors of MEK Dependence in Non–Small Cell Lung Cancer

Christine A. Pratilas, Aphrothiti J. Hanrahan, Ensar Halilovic et al. · Cancer Research · 2008 · 254 citations · Full text

Medicine, Genetics, Oncology +17

Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF

Fangrong Xing, Yogindra Persaud, Christine A. Pratilas et al. · Oncogene · 2011 · 203 citations · Full text

Medicine, Molecular Biology, Oncology +17