Steven R. Whittaker

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Sonja J. Heidorn, Carla Milagre, Steven R. Whittaker et al. · Cell · 2010 · 1.5K citations · Full text

The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

Eliezer M. Van Allen, Nikhil Wagle, Antje Sucker et al. · Cancer Discovery · 2013 · 927 citations · Full text

Engineering, Raf Kinase Inhibitors, Pathology +18

A Genome-Scale RNA Interference Screen Implicates NF1 Loss in Resistance to RAF Inhibition

Steven R. Whittaker, Jean‐Philippe Theurillat, Eliezer M. Van Allen et al. · Cancer Discovery · 2013 · 345 citations · Full text

Melanoma Tumors, Genetics, Genomic Mechanism +19

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

María Romina Girotti, Filipa M. Lopes, Natasha Preece et al. · Cancer Cell · 2014 · 201 citations · Full text

The Cyclin-dependent Kinase Inhibitor CYC202 (<b><i>R</i></b>-Roscovitine) Inhibits Retinoblastoma Protein Phosphorylation, Causes Loss of Cyclin D1, and Activates the Mitogen-activated Protein Kinase Pathway

Steven R. Whittaker, Mike I. Walton, Michelle D. Garrett et al. · Cancer Research · 2004 · 192 citations · Full text