Kinase bypass: A new strategy for anti-HIV drug design

HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged Therapy

B. A. Larder, G. Darby, Douglas D. Richman · Science · 1989 · 1.6K citations

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

Viral Replication, Thymidine Analog, Immunology +18

Multiple Mutations in HIV-1 Reverse Transcriptase Confer High-Level Resistance to Zidovudine (AZT)

Brendan Larder, Sharon D. Kemp · Science · 1989 · 1.2K citations

3'-Substituted 2',3'-dideoxynucleoside analogs as potential anti-HIV (HTLV-III/LAV) agents

Piet Herdewijn, Jan Balzarini, Erik De Clercq et al. · Journal of Medicinal Chemistry · 1987 · 295 citations

Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

Christopher McGuigan, Ranjith Pathirana, Naheed Mahmood et al. · Antiviral Research · 1992 · 152 citations

Medicinal Chemistry, Medicine, Human Retrovirus +8