Erik De Clercq

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Life Sciences, Infectious Diseases, Analytical Chemistry +12

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

Paola Bezzi, Marı́a Domercq, Liliana Brambilla et al. · Nature Neuroscience · 2001 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +14

A novel selective broad-spectrum anti-DNA virus agent

Erik De Clercq, Ivan Rosenberg, Takashi Sakuma et al. · Nature · 1986 · 764 citations

Pharmacy, Medicinal Chemistry, Microbiology +9

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor

G A Donzella, Dominique Schols, Steven Lin et al. · Nature Medicine · 1998 · 763 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 757 citations

Medicine, Medicinal Chemistry, Pharmacology +12