Jan Desmyter

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Medicinal Chemistry, Bioassay-guided Isolation, Tetrazolium-based Colorimetric Assay +12

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 754 citations

Selective Inhibition, Medicinal Chemistry, Medicine +11

Defectiveness of Interferon Production and of Rubella Virus Interference in a Line of African Green Monkey Kidney Cells (Vero)

Jan Desmyter, Joseph L. Melnick, William E. Rawls · Journal of Virology · 1968 · 511 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +13

Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

Masanori Baba, Rudi Pauwels, Jan Balzarini et al. · Proceedings of the National Academy of Sciences · 1988 · 465 citations · Full text

Medicine, Human Retrovirus, Immunology +13

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Medicinal Chemistry, Medicine, Drug Discovery +9