Jan Desmyter

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Life Sciences, Infectious Diseases, Analytical Chemistry +12

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 757 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Defectiveness of Interferon Production and of Rubella Virus Interference in a Line of African Green Monkey Kidney Cells (Vero)

Jan Desmyter, Joseph L. Melnick, William E. Rawls · Journal of Virology · 1968 · 517 citations · Full text

Life Sciences, Cell Biology, Microbiology +14

Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

Masanori Baba, Rudi Pauwels, Jan Balzarini et al. · Proceedings of the National Academy of Sciences · 1988 · 466 citations · Full text

Medicine, Immunology, Pharmacology +7

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13