Rudi Pauwels

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Medicinal Chemistry, Bioassay-guided Isolation, Tetrazolium-based Colorimetric Assay +12

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 754 citations

Selective Inhibition, Medicinal Chemistry, Medicine +11

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

Masanori Baba, Robert Snoeck, Rudi Pauwels et al. · Antimicrobial Agents and Chemotherapy · 1988 · 537 citations · Full text

Medicine, Glycobiology, Immunology +13

Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines

Erik De Clercq, Takashi Sakuma, Masanori Baba et al. · Antiviral Research · 1987 · 512 citations

Medicinal Chemistry, Antiviral Activity, Medicine +5

Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants

Kalyan Das, Arthur D. Clark, Paul Lewi et al. · Journal of Medicinal Chemistry · 2004 · 511 citations