Characterization of Th17 responses to Streptococcus pneumoniae in humans: Comparisons between adults and children in a developed and a developing country

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Spencer C. Liang, Xiangyang Tan, Deborah Luxenberg et al. · The Journal of Experimental Medicine · 2006 · 2.3K citations · Full text

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Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells

Eva V. Acosta Rodríguez, Giorgio Napolitani, Antonio Lanzavecchia et al. · Nature Immunology · 2007 · 1.8K citations

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IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

Shean Aujla, Yvonne R. Chan, Mingquan Zheng et al. · Nature Medicine · 2008 · 1.2K citations · Full text

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Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

Thomas Duhen, Rebekka Geiger, David Jarrossay et al. · Nature Immunology · 2009 · 1.1K citations

Life Sciences, Cell Biology, Immunology +16

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

Sara Trifari, Charles D. Kaplan, Elise H. Tran et al. · Nature Immunology · 2009 · 997 citations

Life Sciences, Cell Biology, Immunology +17