Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells

Eva V. Acosta Rodríguez, Giorgio Napolitani, Antonio Lanzavecchia, +1

Nature Immunology

InflammationCytokineLymphocyte DevelopmentImmune Cell DevelopmentImmunology +9

Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

Eva V. Acosta Rodríguez, Laura Rivino, Jens Geginat, +5

Nature Immunology

Adaptive Immune SystemImmune Cell DevelopmentImmunologyImmunodominanceAntigenic Specificity +10

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Yanchun Peng, Alexander J. Mentzer, Guihai Liu, +67

Nature Immunology

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells

Giorgio Napolitani, Andrea Rinaldi, Francesco Bertoni, +2

Nature Immunology

InflammationToll-like ReceptorsT Helper TypeAdaptive Immune SystemInnate Immune System +9

Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells

David Jarrossay, Giorgio Napolitani, Marco Colonna, +2

European Journal of Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyImmune SystemImmunotherapy +21

Anthrax Lethal Factor Cleaves the N-Terminus of MAPKKs and Induces Tyrosine/Threonine Phosphorylation of MAPKs in Cultured Macrophages

Gaetano Vitale, Rossella Pellizzari, Chiara Recchi, +3

Biochemical and Biophysical Research Communications

InflammationSignal TransductionInduces Tyrosine/threonine PhosphorylationSignaling PathwayReceptor Tyrosine Kinase +11

Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

Gaetano Vitale, L. Bernardi, Giorgio Napolitani, +2

Biochemical Journal

Family MembersApoptosisMolecular BiologyAnthrax Lethal FactorConsensus Motifs +14

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

David Ahern, Zhichao Ai, Mark Ainsworth, +202

Cell

Single-cell atlas of colonic CD8+ T cells in ulcerative colitis

Daniele Corridoni, Agne Antanaviciute, Tarun Gupta, +17

Nature Medicine

InflammationAutoimmune DiseaseMucosal ImmunologyT-regulatory CellImmunology +6

Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate

Carmen G. Palii, Qian Cheng, Mark A. Gillespie, +8

Cell stem cell

Transcriptional RegulationQuantitative ChangesDevelopmental BiologyFunctional GenomicsCell Lineage +11