IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

Shean Aujla, Yvonne R. Chan, Mingquan Zheng, +15

Nature Medicine

InflammationHost ResponseMucosal ImmunologyLung InflammationInnate Immune System +4

Lipocalin 2 Is Required for Pulmonary Host Defense against <i>Klebsiella</i> Infection

Yvonne R. Chan, Jessica S. Liu, Derek Pociask, +8

The Journal of Immunology

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationKlebsiella PneumoniaeImmunology +16

Liver is the major source of elevated serum lipocalin‐2 levels after bacterial infection or partial hepatectomy: A critical role for IL‐6/STAT3

Ming‐Jiang Xu, Dechun Feng, Hailong Wu, +10

Hepatology

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

Mariana Nacht, Andreas Strasser, Yvonne R. Chan, +4

Genes & Development

ApoptosisImmunologyMolecular BiologyCell DeathCancer Biology +17

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

Kong Chen, Derek Pociask, Jeremy P. McAleer, +8

PLoS ONE

AsthmaInflammatory Lung DiseaseImmunologyCigarette SmokeCcl2 Expression +15

Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis

James L. Kreindler, Chad Steele, Nikki Nguyen, +14

Journal of Clinical Investigation

InflammationTh2 ReactivityAllergyInflammatory Lung DiseaseLung Inflammation +13

STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia

Stephanie Poe, Meenakshi Arora, Timothy B. Oriss, +9

Mucosal Immunology

InflammationLung InflammationMedicineImmunologyRespiratory Infection +7

Influenza A Virus Exacerbates Staphylococcus aureus Pneumonia in Mice by Attenuating Antimicrobial Peptide Production

Keven M. Robinson, Kevin J. McHugh, Sivanarayana Mandalapu, +7

The Journal of Infectious Diseases

Dectin-1-Dependent Interleukin-22 Contributes to Early Innate Lung Defense against Aspergillus fumigatus

Melissa A. Gessner, Jessica L. Werner, Lauren Lilly, +8

Infection and Immunity

Il-22 ProductionDectin-1-dependent Interleukin-22 ContributesInflammatory Lung DiseaseAspergillus FumigatusLung Inflammation +20

PR-39, a Syndecan-inducing Antimicrobial Peptide, Binds and Affects p130Cas

Yvonne R. Chan, Richard L. Gallo

Journal of Biological Chemistry