Concepedia

Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: Influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates

Iuri E. Gouvêa, Mario Augusto Izidoro, Wagner Alves de Souza Júdice, Maria Helena S. Cezari, Giuseppe Caliendo, Vincenzo Santagada, Claudia Nunes Duarte dos Santos, María A. Juliano, Paul R. Young, David P. Fairlie,

Archives of Biochemistry and Biophysics · 2006 · 34 citations · 24 references

DOI

Concepts

References

24

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.

T J Chambers, Ronald C. Weir, Arash Grakoui et al. · Proceedings of the National Academy of Sciences · 1990 · 351 citations

, , +17

Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors

Donmienne Leung, Kate Schroder, Helen L. White et al. · Journal of Biological Chemistry · 2001 · 322 citations · Full text

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Purified NS2B/NS3 Serine Protease of Dengue Virus Type 2 Exhibits Cofactor NS2B Dependence for Cleavage of Substrates with Dibasic Amino Acids in Vitro

Rohana Yusof, Stephen Clum, Mary G. Wetzel et al. · Journal of Biological Chemistry · 2000 · 297 citations · Full text

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α <sub>1</sub> -Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent

François Jean, Kori Stella, Laurel Thomas et al. · Proceedings of the National Academy of Sciences · 1998 · 268 citations · Full text

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Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries

Jun Li, Siew Pheng Lim, David Beer et al. · Journal of Biological Chemistry · 2005 · 249 citations · Full text

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