Concepedia

Protease Cleavage Specificity

Protease Cleavage Specificity is a biochemical property that defines the selective recognition and hydrolysis of peptide bonds in substrate proteins by a protease, distinctively determined by the amino acid sequence and structural features surrounding the cleavage site.

2.1K

Publications

136.9K

Citations

8.4K

Authors

1.6K

Institutions

Publications per year

2017–2026

171

Parents

Publications

2.1K

Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase

Chad Vickers, Paul Hales, Virendar K. Kaushik et al. · Journal of Biological Chemistry · 2002 · 1.4K citations · Full text

, , +17

Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis

M. Furlan, Rodolfo Robles, B Lamie · Blood · 1996 · 893 citations · Full text

, , +17

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

Susan Gottesman, Eric Roche, Yi Zhou et al. · Genes & Development · 1998 · 857 citations · Full text

, , +12

Cloning and characterization of human protease-activated receptor 4

Wenfeng Xu, Henrik Andersen, Theodore E. Whitmore et al. · Proceedings of the National Academy of Sciences · 1998 · 816 citations

, , +16

Beta-amyloid precursor protein cleavage by a membrane-bound protease.

Sangram S. Sisodia · Proceedings of the National Academy of Sciences · 1992 · 730 citations

, , +17

1–5 of 2.1K

Authors

8.4K

  1. CS
    Charles S. Craik

    University of California, San Francisco, United States

    18 publications · 1.5K citations

    17

    h-index

  2. NG
    Nabil G. Seidah

    Montreal Clinical Research Institute, Canada

    15 publications · 1.2K citations

    15

    h-index

  3. CM
    Christopher M. Overall

    University of British Columbia, Canada

    15 publications · 1.5K citations

    15

    h-index

  4. KG
    Kris Gevaert

    Ghent University, Belgium

    14 publications · 676 citations

    14

    h-index

  5. LJ
    Luiz Juliano

    Universidade Federal de São Paulo, Brazil

    17 publications · 691 citations

    14

    h-index

1–5 of 8.4K

Institutions

1.6K

  1. University of California, San Francisco

    San Francisco, United States

    34 h-index

    144 publications

    11.4K citations

  2. Harvard University

    Cambridge, United States

    31 h-index

    126 publications

    14.1K citations

  3. National Institutes of Health

    Bethesda, United States

    30 h-index

    137 publications

    7.6K citations

  4. Washington University in St. Louis

    St Louis, United States

    29 h-index

    88 publications

    6.8K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    101 publications

    8.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    122 publications

    6.2K citations

  7. Inserm

    Paris, France

    21 h-index

    117 publications

    6.2K citations

  8. University of British Columbia

    Vancouver, Canada

    21 h-index

    106 publications

    13.5K citations

1–8 of 1.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 397 publications · 35.8K citations

    106

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 86 publications · 12.2K citations

    58

    h-index

  3. Biochemistry

    97 publications · 5.3K citations

    45

    h-index

  4. Journal of Virology

    JVI · 71 publications · 4.8K citations

    44

    h-index

  5. European Journal of Biochemistry

    EJB · 77 publications · 4K citations

    41

    h-index

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