Donmienne Leung

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

Donmienne Leung, Christophe Hardouin, Dale L. Boger et al. · Nature Biotechnology · 2003 · 385 citations

Proteomic Technology, Complex Proteomes, Biochemistry +10

Inactivation of <i>N</i>-Acyl Phosphatidylethanolamine Phospholipase D Reveals Multiple Mechanisms for the Biosynthesis of Endocannabinoids

Donmienne Leung, Alan Saghatelian, Gabriel M. Simon et al. · Biochemistry · 2006 · 348 citations · Full text

Reversible Inhibitors of Fatty Acid Amide Hydrolase That Promote Analgesia: Evidence for an Unprecedented Combination of Potency and Selectivity

Aron H. Lichtman, Donmienne Leung, Christopher C. Shelton et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 325 citations

Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors

Donmienne Leung, Kate Schroder, Helen L. White et al. · Journal of Biological Chemistry · 2001 · 320 citations · Full text

Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics

Dale L. Boger, Hiroshi Miyauchi, Wu Du et al. · Journal of Medicinal Chemistry · 2004 · 213 citations · Full text

Pharmaceutical Science, Drug Target, Pain Medicine +21